Reactome | MLPH/MYRIP bind GGC-RAB27A and MYO5A

Schema > Reaction > Entries

MLPH/MYRIP bind GGC-RAB27A and MYO5A Show undefined attributes

category	binding
compartment	[Compartment:5668575] melanosome membrane [Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10095356
displayName	MLPH/MYRIP bind GGC-RAB27A and MYO5A
eventOf	[Pathway:R-MMU-9824585] Regulation of MITF-M-dependent genes involved in pigmentation - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9856465] MLPH/MYRIP bind GGC-RAB27A and MYO5A - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-8877281] GGC-RAB27A [melanosome membrane] [DefinedSet:R-MMU-9856440] MLPH,MYRIP [cytosol] [Complex:R-MMU-9605106] p-S1652-MYO5A dimer [cytosol] [EntityWithAccessionedSequence:R-MMU-9856433] Sytl2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MLPH/MYRIP bind GGC-RAB27A and MYO5A
output	[Complex:R-MMU-9856444] GGC-RAB27A:MLPH,MYRIP:SYTL2:p-S1652-MYO5A dimer [melanosome membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9856465
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9824585] Regulation of MITF-M-dependent genes involved in pigmentation
(inferredTo)	[Reaction:R-HSA-9856465] MLPH/MYRIP bind GGC-RAB27A and MYO5A

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