Reactome | FAM83B, (FAM83A, FAM83D) bind EGFR

Schema > Reaction > Entries

FAM83B, (FAM83A, FAM83D) bind EGFR Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10095178
displayName	FAM83B, (FAM83A, FAM83D) bind EGFR
eventOf	[Pathway:R-MMU-177929] Signaling by EGFR - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-177934] EGFR autophosphorylation - Mus musculus
goBiologicalProcess	[GO_BiologicalProcess:24608] positive regulation of epidermal growth factor receptor signaling pathway
inferredFrom	[Reaction:R-HSA-9851407] FAM83B, (FAM83A, FAM83D) bind EGFR - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-179837] EGFR [plasma membrane] [CandidateSet:R-MMU-9851390] FAM83B,(FAM83A, FAM83D) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FAM83B, (FAM83A, FAM83D) bind EGFR
output	[Complex:R-MMU-9851427] EGFR:FAM83B,(FAM83A, FAM83D) [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9851407
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-177929] Signaling by EGFR
(precedingEvent)	[Reaction:R-MMU-177934] EGFR autophosphorylation
(inferredTo)	[Reaction:R-HSA-9851407] FAM83B, (FAM83A, FAM83D) bind EGFR

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