Reactome | ST8SIA5 transfers Neu5Ac to gangliosides

Schema > Reaction > Entries

ST8SIA5 transfers Neu5Ac to gangliosides Show undefined attributes

catalystActivity	[CatalystActivity:10095147] alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity of ST8SIA5 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10095149
displayName	ST8SIA5 transfers Neu5Ac to gangliosides
eventOf	[Pathway:R-MMU-9840309] Glycosphingolipid biosynthesis - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9845587] ST8SIA5 transfers Neu5Ac to gangliosides - Homo sapiens
input	[SimpleEntity:R-ALL-727815] CMP-Neu5Ac [Golgi lumen] [DefinedSet:R-ALL-9845581] GM1b,GD1a,GD3,GT1b [Golgi membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	ST8SIA5 transfers Neu5Ac to gangliosides
output	[SimpleEntity:R-ALL-727810] CMP [Golgi lumen] [DefinedSet:R-ALL-9845591] GQ1b,GT3,GD1c,GT1a [Golgi membrane] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9845587
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9840309] Glycosphingolipid biosynthesis
(inferredTo)	[Reaction:R-HSA-9845587] ST8SIA5 transfers Neu5Ac to gangliosides

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