Reactome | ST3GAL5 transfers NeuNAc to ceramides

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ST3GAL5 transfers NeuNAc to ceramides Show undefined attributes

catalystActivity	[CatalystActivity:10095122] beta-galactoside (CMP) alpha-2,3-sialyltransferase activity of ST3GAL5 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10095124
displayName	ST3GAL5 transfers NeuNAc to ceramides
eventOf	[Pathway:R-MMU-9840309] Glycosphingolipid biosynthesis - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9844860] ST3GAL5 transfers NeuNAc to ceramides - Homo sapiens
input	[SimpleEntity:R-ALL-727815] CMP-Neu5Ac [Golgi lumen] [DefinedSet:R-ALL-9844855] LacCer/GalCer/GA1/GA2 [Golgi membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	ST3GAL5 transfers NeuNAc to ceramides
output	[SimpleEntity:R-ALL-727810] CMP [Golgi lumen] [DefinedSet:R-ALL-9844871] GM1/2/3/4 [Golgi membrane] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen]
precedingEvent	[Reaction:R-MMU-6785933] UGT8 transfers Gal from UDP-Gal to CERA - Mus musculus [Reaction:R-MMU-727807] SLC35A1 exchanges CMP-Neu5Ac for CMP - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9844860
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9840309] Glycosphingolipid biosynthesis
(inferredTo)	[Reaction:R-HSA-9844860] ST3GAL5 transfers NeuNAc to ceramides

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