Reactome | AKT3 phosphorylates TBX3

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AKT3 phosphorylates TBX3 Show undefined attributes

catalystActivity	[CatalystActivity:10093732] protein serine/threonine kinase activity of p-T305,S472-AKT3 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10093734
displayName	AKT3 phosphorylates TBX3
eventOf	[Pathway:R-MMU-9856649] Transcriptional and post-translational regulation of MITF-M expression and activity - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9825704] AKT3 phosphorylates TBX3 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9825678] Tbx3 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	AKT3 phosphorylates TBX3
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9825680] phospho-Tbx3 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9825704
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9856649] Transcriptional and post-translational regulation of MITF-M expression and activity
(inferredTo)	[Reaction:R-HSA-9825704] AKT3 phosphorylates TBX3