Reactome | Mixl1 binds the Gsc gene

Schema > Reaction > Entries

authored	[InstanceEdit:9823884] May, Bruce, 2023-01-11
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9823972] May, Bruce, 2023-01-13
dbId	9823983
displayName	Mixl1 binds the Gsc gene
edited	[InstanceEdit:9823884] May, Bruce, 2023-01-11
input	[EntityWithAccessionedSequence:R-MMU-9756940] Gsc gene [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9758504] Mixl1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9823854] Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation [LiteratureReference:9830205] Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells
maxDepth	1
modified	[InstanceEdit:9830227] May, Bruce, 2023-02-28
name	Mixl1 binds the Gsc gene
orthologousEvent	[Reaction:R-HSA-9823966] EOMES, SMAD2,3, MIXL1 bind the GSC gene - Homo sapiens
output	[Complex:R-MMU-9823967] Mixl1:Gsc gene [nucleoplasm]
releaseDate	2023-03-29
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9830224] Salehin, Nazmus, 2023-02-28 [InstanceEdit:9830223] Tam, Patrick P L, 2023-02-28
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9823983
summation	[Summation:9825103] Mixl1 binds two elements in the promoter of the Gsc gene (Li...

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