Reactome | Expression of Sox17 in definitive endoderm

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Expression of Sox17 in definitive endoderm Show undefined attributes

authored	[InstanceEdit:9823732] May, Bruce, 2023-01-08
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9823728] May, Bruce, 2023-01-08
dbId	9823745
displayName	Expression of Sox17 in definitive endoderm
edited	[InstanceEdit:9823732] May, Bruce, 2023-01-08
input	[EntityWithAccessionedSequence:R-MMU-9823743] Sox17 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9823727] Wnt/?-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse [LiteratureReference:9823854] Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation [LiteratureReference:9823867] Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development [LiteratureReference:9794956] Charting Brachyury-mediated developmental pathways during early mouse embryogenesis [LiteratureReference:9823949] SOX17 links gut endoderm morphogenesis and germ layer segregation [LiteratureReference:9823877] Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos [LiteratureReference:9825101] Dissecting the molecular hierarchy for mesendoderm differentiation through a combination of embryonic stem cell culture and RNA interference [LiteratureReference:9758914] Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo
maxDepth	1
modified	[InstanceEdit:9830227] May, Bruce, 2023-02-28
name	Expression of Sox17 in definitive endoderm
orthologousEvent	[BlackBoxEvent:R-HSA-9823729] Expression of SOX17 in definitive endoderm - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-9823740] Sox17 [nucleoplasm]
regulatedBy	[PositiveGeneExpressionRegulation:9823850] Positive gene expression regulation by 'Tcf7l2:Ctnnb1:Foxa2:Tbxt:Gata4:Sox17 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9823871] Positive gene expression regulation by 'Mixl1 [nucleoplasm]'
regulationReference	[RegulationReference:9823862] Positive gene expression regulation by 'Tcf7l2:Ctnnb1:Foxa2:Tbxt:Gata4:Sox17 gene [nucleoplasm]' Wnt/?-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse [RegulationReference:9823846] Positive gene expression regulation by 'Mixl1 [nucleoplasm]' Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation
releaseDate	2023-03-29
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9830224] Salehin, Nazmus, 2023-02-28 [InstanceEdit:9830223] Tam, Patrick P L, 2023-02-28
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9823745
summation	[Summation:9823839] Sox17 is first expressed in the visceral endoderm, then in p...

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