Reactome | Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1 [cytosol]

Schema > Complex > Entries

Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-9763880] Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1:p-Y-Cbl [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9817994] Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1 binds Cbl - Mus musculus [Reaction:R-MMU-9763903] Csf1 dimer:p-Y559-Csf1r dimer binds Grb2:Sos1 - Mus musculus
created	[InstanceEdit:9817989] May, Bruce, 2022-10-08
dbId	9817993
displayName	Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1 [cytosol]
hasComponent	[Complex:R-MMU-9763885] Csf1 dimer:p-Y559-Csf1r dimer [plasma membrane] [DefinedSet:R-MMU-9817999] Fyn,Hck,Src,Yes1 [cytosol]
inDisease	false
includedLocation	[Compartment:984] extracellular region [Compartment:876] plasma membrane
isChimeric	false
literatureReference	[LiteratureReference:9681133] A juxtamembrane tyrosine in the colony stimulating factor-1 receptor regulates ligand-induced Src association, receptor kinase function, and down-regulation [LiteratureReference:9817998] Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors [LiteratureReference:9818002] Expression of a Y559F mutant CSF-1 receptor in M1 myeloid cells: a role for Src kinases in CSF-1 receptor-mediated differentiation
maxDepth	4
name	Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1
producedByEvent	[Reaction:R-MMU-9818009] Csf1 dimer:p-Y559-Csf1r dimer binds Src family kinases Fyn,Hck,Src,Yes1 - Mus musculus [Reaction:R-MMU-9764150] Csf1 dimer:p-Y-559-Csf1r dimer:SFK:Grb2:Sos1 dissociates yielding Csf1 dimer:p-Y-559-Csf1r dimer:SFK and Grb2:Sos1 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-9817993

Referrals

(hasComponent)	[Complex:R-MMU-9763880] Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1:p-Y-Cbl [plasma membrane] [Complex:R-MMU-9763898] Csf1 dimer:p-Y-559-Csf1r:Fyn,Hck,Src,Yes1:Cbl [plasma membrane] [Complex:R-MMU-9763900] Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1:Grb2:Sos1 [plasma membrane]
(input)	[Reaction:R-MMU-9817994] Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1 binds Cbl [Reaction:R-MMU-9763903] Csf1 dimer:p-Y559-Csf1r dimer binds Grb2:Sos1
(output)	[Reaction:R-MMU-9764150] Csf1 dimer:p-Y-559-Csf1r dimer:SFK:Grb2:Sos1 dissociates yielding Csf1 dimer:p-Y-559-Csf1r dimer:SFK and Grb2:Sos1 [Reaction:R-MMU-9818009] Csf1 dimer:p-Y559-Csf1r dimer binds Src family kinases Fyn,Hck,Src,Yes1

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