Reactome | Tead2,Tead4:Yap1 and Tbxt bind the Foxa2 gene

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Tead2,Tead4:Yap1 and Tbxt bind the Foxa2 gene Show undefined attributes

authored	[InstanceEdit:9796305] May, Bruce, 2022-08-08
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9796202] May, Bruce, 2022-08-09
dbId	9796226
displayName	Tead2,Tead4:Yap1 and Tbxt bind the Foxa2 gene
edited	[InstanceEdit:9796305] May, Bruce, 2022-08-08
input	[EntityWithAccessionedSequence:R-MMU-9796265] Foxa2 gene [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9733724] Tbxt [nucleoplasm] [DefinedSet:R-MMU-9796247] Tead2:Yap1,Tead4:Yap1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9796281] Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor [LiteratureReference:9794956] Charting Brachyury-mediated developmental pathways during early mouse embryogenesis [LiteratureReference:9756934] Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-? signaling
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Tead2,Tead4:Yap1 and Tbxt bind the Foxa2 gene
orthologousEvent	[Reaction:R-HSA-9796225] TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene - Homo sapiens
output	[Complex:R-MMU-9796297] Tead2,Tead4:Yap1:Tbxt:Foxa2 gene [nucleoplasm]
releaseDate	2022-12-07
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9818412] Sasaki, Hiroshi, 2022-10-15
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9796226
summation	[Summation:9796286] Tead proteins (Tead2 and Tead4 and possibly Tead1 and Tead3)...

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