Reactome | Cflar [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10093180
displayName	Cflar [cytosol]
endCoordinate	480
hasModifiedResidue	[GroupModifiedResidue:10093177] ubiquitinylated lysine (M1polyUb [cytosol]) at 351 (in Homo sapiens) [GroupModifiedResidue:10093178] ubiquitinylated lysine (M1polyUb [cytosol]) at 353 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-9794015] M1polyUb-K351,K353-CFLAR(1-480) [cytosol] - Homo sapiens
maxDepth	1
name	Cflar M1polyUb-K351,K353-CFLAR(1-480) O35732
producedByEvent	[BlackBoxEvent:R-MMU-9793988] LUBAC ubiquitinates CFLAR at K351, K353 - Mus musculus
referenceEntity	[ReferenceGeneProduct:uniprot:O35732] UniProt:O35732
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-9794015
startCoordinate	1

(output)	[BlackBoxEvent:R-MMU-9793988] LUBAC ubiquitinates CFLAR at K351, K353
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-9794015] M1polyUb-K351,K353-CFLAR(1-480) [cytosol]

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