Reactome | AKR1E2 reduces 1,5-aF to 1,5-aG

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AKR1E2 reduces 1,5-aF to 1,5-aG Show undefined attributes

catalystActivity	[CatalystActivity:10093114] 1,5-anhydro-D-fructose reductase activity of AKR1E2 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10093116
displayName	AKR1E2 reduces 1,5-aF to 1,5-aG
eventOf	[Pathway:R-MMU-70221] Glycogen breakdown (glycogenolysis) - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9773976] AKR1E2 reduces 1,5-aF to 1,5-aG - Homo sapiens
input	[SimpleEntity:R-ALL-9773955] 1,5-aF [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AKR1E2 reduces 1,5-aF to 1,5-aG 1,5-anhydro-D-fructose + NADPH + H(+) => 1,5-anhydro-D-glucitol + NADP(+)
output	[SimpleEntity:R-ALL-9773958] 1,5-aG [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9773976
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-70221] Glycogen breakdown (glycogenolysis)
(inferredTo)	[Reaction:R-HSA-9773976] AKR1E2 reduces 1,5-aF to 1,5-aG

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