Reactome | Glycogen breakdown (glycogenolysis)

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Glycogen breakdown (glycogenolysis) Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10098577
displayName	Glycogen breakdown (glycogenolysis)
eventOf	[Pathway:R-MMU-8982491] Glycogen metabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-MMU-71336] Pentose phosphate pathway - Mus musculus
goBiologicalProcess	[GO_BiologicalProcess:19492] glycogen catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-71541] glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP - Mus musculus [Reaction:R-MMU-71588] glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP - Mus musculus [Reaction:R-MMU-453342] PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex - Mus musculus [Reaction:R-MMU-453338] PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP - Mus musculus [Reaction:R-MMU-71552] limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin - Mus musculus [Reaction:R-MMU-71593] ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose - Mus musculus [Reaction:R-MMU-9638125] PGM1:Mg2+ isomerises G1P to G6P - Mus musculus [Reaction:R-MMU-9036727] GAA hydrolyzes lysosomal glycogen - Mus musculus [Reaction:R-MMU-9773976] AKR1E2 reduces 1,5-aF to 1,5-aG - Mus musculus
inferredFrom	[Pathway:R-HSA-70221] Glycogen breakdown (glycogenolysis) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Glycogen breakdown (glycogenolysis)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-70221
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-8982491] Glycogen metabolism
(precedingEvent)	[Pathway:R-MMU-71336] Pentose phosphate pathway
(inferredTo)	[Pathway:R-HSA-70221] Glycogen breakdown (glycogenolysis)