Reactome | Expression of Eomes in the primitive streak

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Expression of Eomes in the primitive streak Show undefined attributes

authored	[InstanceEdit:9754311] May, Bruce, 2021-09-23
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9754482] May, Bruce, 2021-09-28
dbId	9754479
displayName	Expression of Eomes in the primitive streak
edited	[InstanceEdit:9754311] May, Bruce, 2021-09-23
input	[EntityWithAccessionedSequence:R-MMU-9754275] Eomes gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9754476] Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo [LiteratureReference:9754502] Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse [LiteratureReference:9754496] Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation [LiteratureReference:9733737] The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation [LiteratureReference:5251124] Eomesodermin is required for mouse trophoblast development and mesoderm formation [LiteratureReference:9754504] Eomes and Brachyury control pluripotency exit and germ-layer segregation by changing the chromatin state [LiteratureReference:9766079] Expression of the T-box gene Eomesodermin during early mouse development
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of Eomes in the primitive streak
orthologousEvent	[BlackBoxEvent:R-HSA-452353] Expression of EOMES in the primitive streak - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-9733704] Eomes [nucleoplasm]
regulatedBy	[PositiveGeneExpressionRegulation:9754485] Positive gene expression regulation by 'p-2S-Smad2,3:Smad4:Tbpl2:Eomes gene [nucleoplasm]'
regulationReference	[RegulationReference:9754511] Positive gene expression regulation by 'p-2S-Smad2,3:Smad4:Tbpl2:Eomes gene [nucleoplasm]' Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo
releaseDate	2022-06-09
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9773645] Tam, Patrick P L, 2022-05-08 [InstanceEdit:9794593] Probst, Simone, 2022-07-18 [InstanceEdit:9796183] Zissel, Lea, 2022-07-18 [InstanceEdit:9796182] Salehin, Nazmus, 2022-05-08
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9754479
summation	[Summation:9754507] Eomesodermin (Eomes) is expressed in cells of the proximal p...
updateTrackers	[UpdateTracker:9847018] Update Tracker - [BlackBoxEvent:9754479] Expression of Eomes in the primitive streak - v82:[modifyText]

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[UpdateTracker:9847018] Update Tracker - [BlackBoxEvent:9754479] Expression of Eomes in the primitive streak - v82:[modifyText]