Reactome | CYP3A4 binds CYP3A4 inhibitors

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10089757
displayName	CYP3A4 binds CYP3A4 inhibitors
eventOf	[Pathway:R-MMU-211945] Phase I - Functionalization of compounds - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9678766] CYP3A4 binds CYP3A4 inhibitors - Homo sapiens
input	[DefinedSet:R-ALL-9679016] CYP3A4 inhibitors [cytosol] [DefinedSet:R-MMU-52639-9] Homologues of CYP3A4 [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CYP3A4 binds CYP3A4 inhibitors
output	[Complex:R-MMU-9679000] CYP3A4:CYP3A4 inhibitors [endoplasmic reticulum membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9678766
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-211945] Phase I - Functionalization of compounds
(inferredTo)	[Reaction:R-HSA-9678766] CYP3A4 binds CYP3A4 inhibitors

Cite Us!