Reactome | Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub

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Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10088809
displayName	Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub
eventOf	[Pathway:R-MMU-9646399] Aggrephagy - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-9641111] Parkin transfers Ub to misfolded proteins - Mus musculus
inferredFrom	[Reaction:R-HSA-9641096] Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub - Homo sapiens
input	[DefinedSet:R-MMU-9641091] Misfolded Proteins [cytosol] [Complex:R-MMU-9641092] Ub:UBE2N:UBE2V1:PRKN [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub
output	[Complex:R-MMU-9641099] Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol]
precedingEvent	[Reaction:R-MMU-9641089] Parkin binds Ub:UBE2N:UBE2V1 - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9641096
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9646399] Aggrephagy
(precedingEvent)	[Reaction:R-MMU-9641111] Parkin transfers Ub to misfolded proteins
(inferredTo)	[Reaction:R-HSA-9641096] Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub

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