Reactome | HEXB cleaves the terminal GlcNAc from small HA fragments

Schema > Reaction > Entries

HEXB cleaves the terminal GlcNAc from small HA fragments Show undefined attributes

catalystActivity	[CatalystActivity:10088576] beta-N-acetylhexosaminidase activity of bHEXB [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10088580
displayName	HEXB cleaves the terminal GlcNAc from small HA fragments
eventOf	[Pathway:R-MMU-2160916] Hyaluronan degradation - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-2162226] GUSB tetramer hydrolyzes GlcA-?1,3-GlcNAc - Mus musculus
inferredFrom	[Reaction:R-HSA-9638076] HEXB cleaves the terminal GlcNAc from small HA fragments - Homo sapiens
input	[OtherEntity:R-ALL-2162223] GlcNAc-GlcA-GlcNAc [lysosomal lumen] [SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	HEXB cleaves the terminal GlcNAc from small HA fragments
output	[SimpleEntity:R-ALL-2162224] GlcA-?1,3-GlcNAc [lysosomal lumen] [SimpleEntity:R-ALL-1678743] GlcNAc [lysosomal lumen]
precedingEvent	[Reaction:R-MMU-2162227] GUSB tetramer hydrolyses (HA)2 - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9638076
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-2160916] Hyaluronan degradation
(precedingEvent)	[Reaction:R-MMU-2162226] GUSB tetramer hydrolyzes GlcA-?1,3-GlcNAc
(inferredTo)	[Reaction:R-HSA-9638076] HEXB cleaves the terminal GlcNAc from small HA fragments

Cite Us!