Reactome | Prdm9 Binds Recombination Hotspot Motifs in DNA

Schema > Reaction > Entries

Prdm9 Binds Recombination Hotspot Motifs in DNA Show undefined attributes

authored	[InstanceEdit:912374] May, B, 2010-07-02
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:912369] May, B, 2010-07-08
dbId	912383
deleted	[Deleted:9032441] Deletion of instance: 912497 [Deleted:9032440] Deletion of instance: 5334727
displayName	Prdm9 Binds Recombination Hotspot Motifs in DNA
edited	[InstanceEdit:912374] May, B, 2010-07-02
followingEvent	[Reaction:R-MMU-1214198] Prdm9 Trimethylates Histone H3 at Lysine-4 - Mus musculus
input	[OtherEntity:R-ALL-29428] DNA [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-912359] Prdm9 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:912339] PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice [LiteratureReference:913222] Prdm9 controls activation of mammalian recombination hotspots [LiteratureReference:1181361] A mouse speciation gene encodes a meiotic histone H3 methyltransferase [LiteratureReference:1181362] A histone H3 methyltransferase controls epigenetic events required for meiotic prophase
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Prdm9 Binds Recombination Hotspot Motifs in DNA
orthologousEvent	[Reaction:R-HSA-912363] PRDM9 binds recombination hotspot motifs in DNA - Homo sapiens
output	[Complex:R-MMU-912364] PRDM9:DNA Complex [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-MMU-912355] Telomere clustering at the nuclear membrane - Mus musculus
releaseDate	2011-03-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1221628] Bolcun-Filas, E, 2011-02-25 [InstanceEdit:1181360] Cohen, PE, 2011-02-04 [InstanceEdit:1181371] Holloway, JK, 2011-02-04 [InstanceEdit:1221625] Lyndaker, A, 2011-02-25 [InstanceEdit:1181380] Schimenti, JC, 2011-02-04 [InstanceEdit:1221623] Strong, E, 2011-02-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-912383
summation	[Summation:914147] The Prdm9 protein binds to sequences that are hotspots for r...

Referrals

(replacementInstances)	[Deleted:9032441] Deletion of instance: 912497 [Deleted:9032440] Deletion of instance: 5334727
(precedingEvent)	[Reaction:R-MMU-1214198] Prdm9 Trimethylates Histone H3 at Lysine-4

Cite Us!