Reactome | ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s

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ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s Show undefined attributes

catalystActivity	[CatalystActivity:10087443] guanyl-nucleotide exchange factor activity of GPER1:Heterotrimeric G-protein Gs:ESTG [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10087445
displayName	ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s
eventOf	[Pathway:R-MMU-9634597] GPER1 signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9036301] ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s - Homo sapiens
input	[Complex:R-MMU-9036305] GPER1:Heterotrimeric G-protein Gs:ESTG [plasma membrane] [SimpleEntity:R-ALL-29438] GTP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-MMU-9036303] GPER1:Heterotrimeric G-protein Gs (active):ESTG [plasma membrane]
precedingEvent	[Reaction:R-MMU-9036307] GPER:Heterotrimeric G-protein Gs binds ESTG - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9036301
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9634597] GPER1 signaling
(inferredTo)	[Reaction:R-HSA-9036301] ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s

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