Reactome | Bglap gene expression is negatively regulated by Znf521

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Bglap gene expression is negatively regulated by Znf521 Show undefined attributes

authored	[InstanceEdit:9008168] Orlic-Milacic, Marija, 2017-06-07
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9008168] Orlic-Milacic, Marija, 2017-06-07
dbId	9008164
displayName	Bglap gene expression is negatively regulated by Znf521
edited	[InstanceEdit:9016543] Orlic-Milacic, Marija, 2017-08-14
input	[EntityWithAccessionedSequence:R-MMU-8985017] Bglap gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9008133] Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Bglap gene expression is negatively regulated by Znf521
orthologousEvent	[BlackBoxEvent:R-HSA-8877922] BGLAP gene expression is stimulated by RUNX2, WWTR1 and RB1 and inhibited by AR, YAP1 and ZNF521 - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-8985023] Bglap [extracellular region]
regulatedBy	[NegativeRegulation:R-MMU-9008167] Negative regulation by 'Runx2:Znf521:Hdac3 [nucleoplasm]'
regulationReference	[RegulationReference:9642274] Negative regulation by 'Runx2:Znf521:Hdac3 [nucleoplasm]' Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9015314] Ducy, Patricia, 2017-08-04
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9008164
summation	[Summation:9008169] In mouse osteoblasts, transcription from the Bglap (Osteocal...

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