Reactome | Runx2 translocates to the nucleus

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9007998] Orlic-Milacic, Marija, 2017-06-06
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9007998] Orlic-Milacic, Marija, 2017-06-06
dbId	9008009
displayName	Runx2 translocates to the nucleus
edited	[InstanceEdit:9015332] Orlic-Milacic, Marija, 2017-08-09
input	[CandidateSet:R-MMU-9007988] Runx2 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9008010] Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Runx2 translocates to the nucleus
orthologousEvent	[BlackBoxEvent:R-HSA-9007999] RUNX2 translocates to the nucleus - Homo sapiens
output	[CandidateSet:R-MMU-9007832] Runx2 [nucleoplasm]
regulatedBy	[NegativeRegulation:R-MMU-9008001] Negative regulation by 'Runx2:Stat1 [cytosol]'
regulationReference	[RegulationReference:9642429] Negative regulation by 'Runx2:Stat1 [cytosol]' Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9015314] Ducy, Patricia, 2017-08-04
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9008009
summation	[Summation:9008003] Translocation of mouse Runx2 to the nucleus is hindered by b...

Cite Us!