Reactome | IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[BlackBoxEvent:R-MMU-8983983] p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10082619
displayName	IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane]
hasComponent	[Complex:R-MMU-8950255] IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-8950418] phospho-Stat1 [cytosol] [EntityWithAccessionedSequence:R-MMU-8950350] phospho-Stat4 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8952780] IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] - Homo sapiens
maxDepth	4
name	IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4
producedByEvent	[BlackBoxEvent:R-MMU-8950453] JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-8952780
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-MMU-8983983] p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor
(output)	[BlackBoxEvent:R-MMU-8950453] JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4
(inferredTo)	[Complex:R-HSA-8952780] IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane]

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