Reactome | IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-8952780] IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] - Mus musculus [Complex:R-MMU-8952787] STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] - Mus musculus
consumedByEvent	[BlackBoxEvent:R-MMU-8983996] STAT1 and STAT4 associate with IL12RB2:IL6ST receptor - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10082573
displayName	IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane]
hasComponent	[Complex:R-MMU-8950302] IL12RB2:p-JAK2 [plasma membrane] [Complex:R-MMU-622267] IL35 [extracellular region] [Complex:R-MMU-8950664] IL6ST:p-JAK1 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8950255] IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] - Homo sapiens
maxDepth	3
name	IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2
producedByEvent	[BlackBoxEvent:R-MMU-8950405] JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated - Mus musculus [BlackBoxEvent:R-MMU-8983983] p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-8950255
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-MMU-8983983] p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor [BlackBoxEvent:R-MMU-8950405] JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated
(input)	[BlackBoxEvent:R-MMU-8983996] STAT1 and STAT4 associate with IL12RB2:IL6ST receptor
(hasComponent)	[Complex:R-MMU-8952787] STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] [Complex:R-MMU-8952780] IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane]
(inferredTo)	[Complex:R-HSA-8950255] IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane]