Reactome | Events associated with phagocytolytic activity of PMN cells

Schema > Pathway > Entries

Events associated with phagocytolytic activity of PMN cells Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10101351
displayName	Events associated with phagocytolytic activity of PMN cells
eventOf	[Pathway:R-MMU-1222556] ROS and RNS production in phagocytes - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-MMU-6789126] Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) - Mus musculus [Reaction:R-MMU-8933635] Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide - Mus musculus [BlackBoxEvent:R-MMU-6789136] Myeloperoxidase (MPO) binds to the bacterial cell surface - Mus musculus [Reaction:R-MMU-6789031] Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) - Mus musculus [Reaction:R-MMU-8855490] Lactoperoxidase (LPO) produces OSCN- - Mus musculus
inferredFrom	[Pathway:R-HSA-8941413] Events associated with phagocytolytic activity of PMN cells - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Events associated with phagocytolytic activity of PMN cells
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-8941413
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1222556] ROS and RNS production in phagocytes
(inferredTo)	[Pathway:R-HSA-8941413] Events associated with phagocytolytic activity of PMN cells

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