Reactome | MMP2 cleaves OPTC

Schema > Reaction > Entries

MMP2 cleaves OPTC Show undefined attributes

catalystActivity	[CatalystActivity:10081733] metalloendopeptidase activity of MMP2(110-660) [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10081735
displayName	MMP2 cleaves OPTC
eventOf	[Pathway:R-MMU-1474228] Degradation of the extracellular matrix - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8940554] MMP2 cleaves OPTC - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-8940538] Optc [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	MMP2 cleaves OPTC
output	[EntityWithAccessionedSequence:R-MMU-8940520] Optc [extracellular region] [EntityWithAccessionedSequence:R-MMU-8940534] Optc [extracellular region] [EntityWithAccessionedSequence:R-MMU-8942317] Optc [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-8940554
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1474228] Degradation of the extracellular matrix
(inferredTo)	[Reaction:R-HSA-8940554] MMP2 cleaves OPTC