Reactome | GABA synthesis

Schema > Pathway > Entries

GABA synthesis Show undefined attributes

compartment	[Compartment:70101] cytosol [Compartment:917757] clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100483
displayName	GABA synthesis
eventOf	[Pathway:R-MMU-888590] GABA synthesis, release, reuptake and degradation - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:26310] gamma-aminobutyric acid biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-888572] PXLP-K405-GAD1 decarboxylates L-Glu to form GABA - Mus musculus [Reaction:R-MMU-888577] Synthesis of GABA by GAD2 - Mus musculus
inferredFrom	[Pathway:R-HSA-888568] GABA synthesis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	GABA synthesis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-888568
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-888590] GABA synthesis, release, reuptake and degradation
(inferredTo)	[Pathway:R-HSA-888568] GABA synthesis