Reactome | Removal of RNA primer and dissociation of RPA and Dna2

Schema > Reaction > Entries

Removal of RNA primer and dissociation of RPA and Dna2 Show undefined attributes

category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9985599
displayName	Removal of RNA primer and dissociation of RPA and Dna2
eventOf	[Pathway:R-MMU-69166] Removal of the Flap Intermediate - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-69152] Removal of remaining Flap - Mus musculus
inferredFrom	[Reaction:R-HSA-69144] Removal of RNA primer and dissociation of RPA and Dna2 - Homo sapiens
input	[Complex:R-MMU-68466] Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Removal of RNA primer and dissociation of RPA and Dna2
output	[SimpleEntity:R-ALL-164121] AMP [nucleoplasm] [SimpleEntity:R-ALL-418076] CMP [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-68465] DNA2 [nucleoplasm] [SimpleEntity:R-ALL-29626] GMP [nucleoplasm] [Complex:R-MMU-68468] Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] [Complex:R-MMU-68462] RPA heterotrimer [nucleoplasm] [SimpleEntity:R-ALL-418075] UMP [nucleoplasm]
precedingEvent	[Reaction:R-MMU-69142] Recruitment of Dna2 endonuclease - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-69144
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-69166] Removal of the Flap Intermediate
(precedingEvent)	[Reaction:R-MMU-69152] Removal of remaining Flap
(inferredTo)	[Reaction:R-HSA-69144] Removal of RNA primer and dissociation of RPA and Dna2

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