Reactome | Hoxa2 chromatin is activated

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Hoxa2 chromatin is activated Show undefined attributes

authored	[InstanceEdit:6808659] May, Bruce, 2015-11-08 [InstanceEdit:6810137] Rezsohazy, Ren�, 2015-11-15
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6810140] May, Bruce, 2015-11-15
dbId	6810138
displayName	Hoxa2 chromatin is activated
edited	[InstanceEdit:6808659] May, Bruce, 2015-11-08
input	[Complex:R-MMU-5619383] Hoxa2 bivalent chromatin [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-5617950] Kdm6a [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5617993] Epigenomic reorganization of the clustered Hox genes in embryonic stem cells induced by retinoic acid [LiteratureReference:5618004] Saltatory remodeling of Hox chromatin in response to rostrocaudal patterning signals [LiteratureReference:5626755] KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development [LiteratureReference:5690634] Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Hoxa2 chromatin is activated
orthologousEvent	[BlackBoxEvent:R-HSA-6810139] HOXA2 chromatin is activated - Homo sapiens
output	[Complex:R-MMU-6810134] Hoxa2 active chromatin [nucleoplasm] [Complex:R-MMU-5617945] PRC2 (EZH2) [nucleoplasm]
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5693642] Blasi, F, 2015-05-13
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-6810138
summation	[Summation:6810092] As inferred from mouse embryonic stem cells activated by ret...