Reactome | ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex

Schema > Reaction > Entries

ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex Show undefined attributes

category	binding
compartment	[Compartment:6791047] endoplasmic reticulum-Golgi intermediate compartment membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10071854
displayName	ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex
eventOf	[Pathway:R-MMU-6807878] COPI-mediated anterograde transport - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-6807877] ARFGAPs stimulate ARF GTPase activity - Mus musculus
inferredFrom	[Reaction:R-HSA-6807875] ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-373619] Ank1 [cytosol] [DefinedSet:R-MMU-6807832] ARFGAP1,2,3 [cytosol] [CandidateSet:R-MMU-6807816] ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] [DefinedSet:R-MMU-6807812] p24 dimers [endoplasmic reticulum-Golgi intermediate compartment membrane] [Complex:R-MMU-6807822] RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] [Complex:R-MMU-420053] Spectrin tetramer [cytosol] [EntityWithAccessionedSequence:R-MMU-5688558] Ykt6 [endoplasmic reticulum-Golgi intermediate compartment membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex
output	[Complex:R-MMU-6807825] RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane]
precedingEvent	[Reaction:R-MMU-6807872] Active ARF recruits coatomer - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-6807875
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-6807878] COPI-mediated anterograde transport
(precedingEvent)	[Reaction:R-MMU-6807877] ARFGAPs stimulate ARF GTPase activity
(inferredTo)	[Reaction:R-HSA-6807875] ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex