Reactome | NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P

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NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P Show undefined attributes

catalystActivity	[CatalystActivity:10070869] N-acetylglucosamine kinase activity of NAGK dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10070871
displayName	NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P
eventOf	[Pathway:R-MMU-446210] Synthesis of UDP-N-acetyl-glucosamine - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-6803789] AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA - Mus musculus
inferredFrom	[Reaction:R-HSA-6803771] NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-ALL-6803785] GlcNAc, GlcNGc [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-ALL-6803738] GlcNAc-6-P, GlcNGc-6-P [cytosol] 2 × [SimpleEntity:R-ALL-70106] H+ [cytosol]
precedingEvent	[Reaction:R-MMU-6803761] RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-6803771
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-446210] Synthesis of UDP-N-acetyl-glucosamine
(precedingEvent)	[Reaction:R-MMU-6803789] AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA
(inferredTo)	[Reaction:R-HSA-6803771] NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P

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