Reactome | Synthesis of UDP-N-acetyl-glucosamine

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Synthesis of UDP-N-acetyl-glucosamine Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100345
displayName	Synthesis of UDP-N-acetyl-glucosamine
eventOf	[Pathway:R-MMU-446219] Synthesis of substrates in N-glycan biosythesis - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:14887] UDP-N-acetylglucosamine biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-6803761] RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc - Mus musculus [Reaction:R-MMU-6803771] NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P - Mus musculus [Reaction:R-MMU-6803789] AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA - Mus musculus [Reaction:R-MMU-449715] GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P - Mus musculus [Reaction:R-MMU-449734] Acetylation of glucosamine 6-phosphate to GlcNAc6P - Mus musculus [Reaction:R-MMU-446185] Isomerization of GlcNAc6P to GlcNAc1P - Mus musculus [Reaction:R-MMU-446204] GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine - Mus musculus
inferredFrom	[Pathway:R-HSA-446210] Synthesis of UDP-N-acetyl-glucosamine - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Synthesis of UDP-N-acetyl-glucosamine
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-446210
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-446219] Synthesis of substrates in N-glycan biosythesis
(inferredTo)	[Pathway:R-HSA-446210] Synthesis of UDP-N-acetyl-glucosamine

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