Reactome | PIK3C3:PIK3R4 phosphorylates PI to PI3P

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PIK3C3:PIK3R4 phosphorylates PI to PI3P Show undefined attributes

catalystActivity	[CatalystActivity:10067277] 1-phosphatidylinositol-3-kinase activity of PIK3C3:PIK3R4 [phagocytic vesicle membrane]
category	transition
compartment	[Compartment:1222693] phagocytic vesicle membrane [Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10067279
displayName	PIK3C3:PIK3R4 phosphorylates PI to PI3P
eventOf	[Pathway:R-MMU-5668599] RHO GTPases Activate NADPH Oxidases - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6798174] PIK3C3:PIK3R4 phosphorylates PI to PI3P - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-1524165] PI [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PIK3C3:PIK3R4 phosphorylates PI to PI3P
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-1629751] PI3P [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-6798174
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-5668599] RHO GTPases Activate NADPH Oxidases
(inferredTo)	[Reaction:R-HSA-6798174] PIK3C3:PIK3R4 phosphorylates PI to PI3P

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