Reactome | Dis3 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-9933578] RNA exosome [nucleoplasm] - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10066316
displayName	Dis3 [nucleoplasm]
endCoordinate	958
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-6791517] DIS3 [nucleoplasm] - Homo sapiens
isRequired	[Requirement:10066337] Requirement by 'DIS3 [nucleoplasm]'
maxDepth	1
name	Dis3 DIS3 Q9CSH3
positivelyRegulates	[Requirement:10066337] Requirement by 'DIS3 [nucleoplasm]'
referenceEntity	[ReferenceGeneProduct:uniprot:Q9CSH3] UniProt:Q9CSH3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-6791517
startCoordinate	1

(regulator)	[Requirement:10066337] Requirement by 'DIS3 [nucleoplasm]'
(activeUnit)	[CatalystActivity:10097236] 3'-5'-RNA exonuclease activity of RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA [nucleoplasm] [CatalystActivity:10097097] 3'-5'-RNA exonuclease activity of PAXT:PAPOLG:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PAPBN1:RNA exosome [nucleoplasm]
(hasComponent)	[Complex:R-MMU-9933578] RNA exosome [nucleoplasm]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-6791517] DIS3 [nucleoplasm]

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