Reactome | Hoxb1 maintains activation of Hoxb1 chromatin

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Hoxb1 maintains activation of Hoxb1 chromatin Show undefined attributes

authored	[InstanceEdit:5693643] May, Bruce, 2015-05-17 [InstanceEdit:6810137] Rezsohazy, Ren�, 2015-11-15
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5693637] May, Bruce, 2015-05-17
dbId	5693628
displayName	Hoxb1 maintains activation of Hoxb1 chromatin
edited	[InstanceEdit:5693643] May, Bruce, 2015-05-17
input	[Complex:R-MMU-5617983] atRA:Rara,g:Rxra at active Hoxb1 chromatin [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-5617979] Hoxb1 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-5619393] Meis1 [nucleoplasm] [Complex:R-MMU-5693633] Pbx1:Pknox1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5693640] Hoxb1 enhancer and control of rhombomere 4 expression: complex interplay between PREP1-PBX1-HOXB1 binding sites [LiteratureReference:5619296] Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interactions between Prep1, Pbx and Hox proteins [LiteratureReference:6810109] MEIS C termini harbor transcriptional activation domains that respond to cell signaling [LiteratureReference:6810118] The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Hoxb1 maintains activation of Hoxb1 chromatin
orthologousEvent	[BlackBoxEvent:R-HSA-5693644] HOXB1 maintains activation of HOXB1 chromatin - Homo sapiens
output	[Complex:R-MMU-5693632] Hoxb1:Pbx1:Pknox1 and Meis1 at active Hoxb1 chromatin [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-MMU-5617960] Retinoic acid activates Hoxb1 chromatin - Mus musculus
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5693642] Blasi, F, 2015-05-13
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-5693628
summation	[Summation:5693639] In mouse embryos (Ferretti et al. 2000) and embryonal carcin...

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