Reactome | Resolution of D-loop Structures through Holliday Junction Intermediates

Schema > Pathway > Entries

Resolution of D-loop Structures through Holliday Junction Intermediates Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10101303
displayName	Resolution of D-loop Structures through Holliday Junction Intermediates
eventOf	[Pathway:R-MMU-5693537] Resolution of D-Loop Structures - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-5686430] MUS81 binds EME1, EME2 - Mus musculus [Reaction:R-MMU-5686440] MUS81:EME1,EME2 cleaves D-loop - Mus musculus [BlackBoxEvent:R-MMU-5693539] Ligation of DNA and formation of Holliday structures following repair synthesis - Mus musculus [Reaction:R-MMU-5686398] SPIDR binds BLM:TOP3A:RMI1:RMI2 - Mus musculus [Reaction:R-MMU-9853368] FIRRM binds FIGNL1 - Mus musculus [Reaction:R-MMU-9853389] FIGNL1 binds RAD51 - Mus musculus [Reaction:R-MMU-9853376] FIGNL1 binds SPIDR - Mus musculus [Reaction:R-MMU-5686475] SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) - Mus musculus [Reaction:R-MMU-5693584] Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) - Mus musculus
inferredFrom	[Pathway:R-HSA-5693568] Resolution of D-loop Structures through Holliday Junction Intermediates - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Resolution of D-loop Structures through Holliday Junction Intermediates
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-5693568
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-5693537] Resolution of D-Loop Structures
(inferredTo)	[Pathway:R-HSA-5693568] Resolution of D-loop Structures through Holliday Junction Intermediates

© 2026 Reactome

Cite Us!