Reactome | Homology Directed Repair

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10098777
displayName	Homology Directed Repair
eventOf	[Pathway:R-MMU-5693532] DNA Double-Strand Break Repair - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:9344] double-strand break repair via homologous recombination
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-MMU-5693567] HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) - Mus musculus [Pathway:R-MMU-5685939] HDR through MMEJ (alt-NHEJ) - Mus musculus
inferredFrom	[Pathway:R-HSA-5693538] Homology Directed Repair - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	6
name	Homology Directed Repair
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-5693538
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-5693532] DNA Double-Strand Break Repair
(inferredTo)	[Pathway:R-HSA-5693538] Homology Directed Repair

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