Reactome | UIMC1 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-5683388] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:UIMC1:p-S406-FAM175A [nucleoplasm] - Mus musculus
consumedByEvent	[Reaction:R-MMU-5683384] UIMC1 and FAM175A bind DNA DSBs - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9985999
displayName	UIMC1 [nucleoplasm]
endCoordinate	719
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5682574] UIMC1 [nucleoplasm] - Homo sapiens
maxDepth	1
name	UIMC1 Q5U5Q9
producedByEvent	[Reaction:R-MMU-5686685] RIF1 and PAX1IP bind TP53BP1 at DNA DSBs - Mus musculus [Reaction:R-MMU-5684071] RNF4 ubiquitinates MDC1 - Mus musculus
referenceEntity	[ReferenceGeneProduct:uniprot:Q5U5Q9] UniProt:Q5U5Q9
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-5682574
startCoordinate	1

(output)	[Reaction:R-MMU-5686685] RIF1 and PAX1IP bind TP53BP1 at DNA DSBs [Reaction:R-MMU-5684071] RNF4 ubiquitinates MDC1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5682574] UIMC1 [nucleoplasm]
(input)	[Reaction:R-MMU-5683384] UIMC1 and FAM175A bind DNA DSBs
(hasComponent)	[Complex:R-MMU-5683388] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:UIMC1:p-S406-FAM175A [nucleoplasm] [Complex:R-MMU-5683386] BRCA1-A Complex [nucleoplasm] [Complex:R-MMU-5683606] p-4S,2T-BRCA1-A Complex [nucleoplasm] [Complex:R-MMU-5683806] p-5S,2T-BRCA1-A Complex [nucleoplasm]