Reactome | AURKB phosphorylates DIAPH2-2 at kinetochores

Schema > Reaction > Entries

AURKB phosphorylates DIAPH2-2 at kinetochores Show undefined attributes

catalystActivity	[CatalystActivity:10058882] protein serine/threonine kinase activity of Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10058884
displayName	AURKB phosphorylates DIAPH2-2 at kinetochores
eventOf	[Pathway:R-MMU-5663220] RHO GTPases Activate Formins - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5666160] AURKB phosphorylates DIAPH2-2 at kinetochores - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-MMU-5666131] Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AURKB phosphorylates DIAPH2-2 at kinetochores
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-MMU-5666161] Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol]
precedingEvent	[Reaction:R-MMU-5666129] CDC42:GTP recruits DIAPH2-2 to kinetochores - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5666160
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-5663220] RHO GTPases Activate Formins
(inferredTo)	[Reaction:R-HSA-5666160] AURKB phosphorylates DIAPH2-2 at kinetochores

Cite Us!