Reactome | FMNL2 binds CDC42:GTP

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10058730
displayName	FMNL2 binds CDC42:GTP
eventOf	[Pathway:R-MMU-5663220] RHO GTPases Activate Formins - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-5665751] CDC42:GTP:FMNL2 binds Profilin:G-actin - Mus musculus
inferredFrom	[Reaction:R-HSA-5665727] FMNL2 binds CDC42:GTP - Homo sapiens
input	[Complex:R-MMU-448879] Cdc42:GTP [plasma membrane] [Complex:R-MMU-5665952] FMNL2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FMNL2 binds CDC42:GTP
output	[Complex:R-MMU-5665735] CDC42:GTP:FMNL2 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5665727
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-5663220] RHO GTPases Activate Formins
(precedingEvent)	[Reaction:R-MMU-5665751] CDC42:GTP:FMNL2 binds Profilin:G-actin
(inferredTo)	[Reaction:R-HSA-5665727] FMNL2 binds CDC42:GTP

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