Reactome | Expression of Npas2

Schema > BlackBoxEvent > Entries

Expression of Npas2 Show undefined attributes

authored	[InstanceEdit:5663195] May, Bruce, 2015-01-15
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:5663250] May, Bruce, 2015-01-16
dbId	5663263
deleted	[Deleted:9032444] Deletion of instance: 1368092 [Deleted:9032440] Deletion of instance: 5334727
displayName	Expression of Npas2
edited	[InstanceEdit:5663195] May, Bruce, 2015-01-15
input	[EntityWithAccessionedSequence:R-MMU-5663254] Npas2 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1368104] RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR [LiteratureReference:1368121] Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism [LiteratureReference:1368152] Characterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target gene
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of Npas2
orthologousEvent	[BlackBoxEvent:R-HSA-1368065] RORA and PPARA positively regulate and NR1D1 negatively regulates expression of NPAS2 - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-508743] Npas2 [cytosol]
precedingEvent	[Reaction:R-MMU-5663256] Rora and Ep300 bind Npas2 gene - Mus musculus
regulatedBy	[PositiveRegulation:R-MMU-5663301] Positive regulation by 'Rora:Ep300:Npas2 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-MMU-5667073] Negative gene expression regulation by 'Nr1d1:heme:Corepressors:Npas2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9641224] Positive regulation by 'Rora:Ep300:Npas2 gene [nucleoplasm]' Characterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target gene
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2084235] Delaunay, F, 2012-01-28
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-5663263
summation	[Summation:5663267] The Npas2 gene is transcribed to yield mRNA and the mRNA is ...

Referrals

(replacementInstances)