Reactome | Signaling by FGFR2

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Signaling by FGFR2 Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10099515
displayName	Signaling by FGFR2
eventOf	[Pathway:R-MMU-190236] Signaling by FGFR - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:24611] fibroblast growth factor receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-MMU-6803529] FGFR2 alternative splicing - Mus musculus [Pathway:R-MMU-190241] FGFR2 ligand binding and activation - Mus musculus [Pathway:R-MMU-5654696] Downstream signaling of activated FGFR2 - Mus musculus [Pathway:R-MMU-5654727] Negative regulation of FGFR2 signaling - Mus musculus
inferredFrom	[Pathway:R-HSA-5654738] Signaling by FGFR2 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Signaling by FGFR2 Fibroblast Growth Factor Receptor (FGFR) signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-5654738
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEncapsulatedEvent)	[Pathway:R-MMU-5673001] RAF/MAP kinase cascade
(inferredTo)	[Pathway:R-HSA-5654738] Signaling by FGFR2
(hasEvent)	[Pathway:R-MMU-190236] Signaling by FGFR

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