Reactome | Ragulator binds Rag dimers

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Ragulator binds Rag dimers Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:17938] lysosomal membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10057886
displayName	Ragulator binds Rag dimers
eventOf	[Pathway:R-MMU-165159] MTOR signalling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-8952716] SLC38A9 binds Ragulator:Rag dimers - Mus musculus
inferredFrom	[Reaction:R-HSA-5653974] Ragulator binds Rag dimers - Homo sapiens
input	[Complex:R-MMU-5653945] RagA,B:GTP:RagC,D:GDP [cytosol] [Complex:R-MMU-5653921] Ragulator [lysosomal membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Ragulator binds Rag dimers
output	[Complex:R-MMU-5653979] Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane]
precedingEvent	[Reaction:R-MMU-5653936] Formation of Ragulator complex - Mus musculus [Reaction:R-MMU-5653957] Rag dimer formation - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5653974
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-165159] MTOR signalling
(precedingEvent)	[Reaction:R-MMU-8952716] SLC38A9 binds Ragulator:Rag dimers
(inferredTo)	[Reaction:R-HSA-5653974] Ragulator binds Rag dimers

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