Reactome | Ragulator [lysosomal membrane]

Schema > Complex > Entries

compartment	[Compartment:17938] lysosomal membrane
componentOf	[Complex:R-MMU-9640171] v-ATPase:Ragulator [lysosomal membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-5653974] Ragulator binds Rag dimers - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9996282
displayName	Ragulator [lysosomal membrane]
hasComponent	[EntityWithAccessionedSequence:R-MMU-5653582] Lamtor1 [lysosomal membrane] [EntityWithAccessionedSequence:R-MMU-5653583] Lamtor2 [lysosomal membrane] [EntityWithAccessionedSequence:R-MMU-5653581] Lamtor3 [lysosomal membrane] [EntityWithAccessionedSequence:R-MMU-5655432] Lamtor4 [lysosomal membrane] [EntityWithAccessionedSequence:R-MMU-5655441] Lamtor5 [lysosomal membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-5653921] Ragulator [lysosomal membrane] - Homo sapiens
maxDepth	2
name	Ragulator
producedByEvent	[Reaction:R-MMU-5653936] Formation of Ragulator complex - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-5653921
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(activeUnit)	[CatalystActivity:10088653] guanyl-nucleotide exchange factor activity of v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane]
(hasComponent)	[Complex:R-MMU-9640171] v-ATPase:Ragulator [lysosomal membrane] [Complex:R-MMU-5653979] Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane]
(input)	[Reaction:R-MMU-5653974] Ragulator binds Rag dimers
(output)	[Reaction:R-MMU-5653936] Formation of Ragulator complex
(inferredTo)	[Complex:R-HSA-5653921] Ragulator [lysosomal membrane]