Reactome | Hoxb1 gene is transcribed

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Hoxb1 gene is transcribed Show undefined attributes

authored	[InstanceEdit:5617898] May, Bruce, 2014-08-15 [InstanceEdit:6810137] Rezsohazy, Ren�, 2015-11-15
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:5617923] May, Bruce, 2014-08-16
dbId	5617972
displayName	Hoxb1 gene is transcribed
edited	[InstanceEdit:5617898] May, Bruce, 2014-08-15
followingEvent	[BlackBoxEvent:R-MMU-5617982] Hoxb1 mRNA is translated - Mus musculus
input	[EntityWithAccessionedSequence:R-MMU-5617995] Hoxb1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5618003] Hox cluster polarity in early transcriptional availability: a high order regulatory level of clustered Hox genes in the mouse [LiteratureReference:5617910] Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning [LiteratureReference:5617966] Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells [LiteratureReference:5617936] Retinoic acid-responsive enhancers located 3' of the Hox A and Hox B homeobox gene clusters. Functional analysis [LiteratureReference:5617967] Evidence for two distinct retinoic acid response pathways for HOXB1 gene regulation [LiteratureReference:5617933] A retinoic acid-triggered cascade of HOXB1 gene activation [LiteratureReference:5617968] Analysis of two distinct retinoic acid response elements in the homeobox gene Hoxb1 in transgenic mice [LiteratureReference:5617918] Functional dissection of a transcriptionally active, target-specific Hox-Pbx complex [LiteratureReference:5619290] Role of a conserved retinoic acid response element in rhombomere restriction of Hoxb-1 [LiteratureReference:5619198] A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1 [LiteratureReference:5675616] Expression of Hoxb genes in the developing mouse foregut and lung [LiteratureReference:5675602] Segment-specific expression of a homoeobox-containing gene in the mouse hindbrain [LiteratureReference:5675609] Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain [LiteratureReference:5688580] Hoxb1 neural crest preferentially form glia of the PNS [LiteratureReference:5688668] Hoxb3 negatively regulates Hoxb1 expression in mouse hindbrain patterning [LiteratureReference:6810109] MEIS C termini harbor transcriptional activation domains that respond to cell signaling [LiteratureReference:6810118] The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Hoxb1 gene is transcribed
orthologousEvent	[BlackBoxEvent:R-HSA-5617454] HOXB1 gene is transcribed - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-5617975] Hoxb1 mRNA [cytosol]
precedingEvent	[BlackBoxEvent:R-MMU-5617960] Retinoic acid activates Hoxb1 chromatin - Mus musculus
regulatedBy	[PositiveRegulation:R-MMU-5634086] Positive regulation by 'atRA:Rara,g:Rxra at active Hoxb1 chromatin [nucleoplasm]'
regulationReference	[RegulationReference:9641469] Positive regulation by 'atRA:Rara,g:Rxra at active Hoxb1 chromatin [nucleoplasm]' A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5693642] Blasi, F, 2015-05-13
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-5617972
summation	[Summation:5621671] The Hoxb1 gene is transcribed to yield mRNA (Marshall et al....

Referrals

(precedingEvent)

[BlackBoxEvent:R-MMU-5617982] Hoxb1 mRNA is translated

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