Reactome | Rarg:Rxra at Hoxa1 bivalent chromatin [nucleoplasm]

Schema > Complex > Entries

Rarg:Rxra at Hoxa1 bivalent chromatin [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[BlackBoxEvent:R-MMU-5617990] Retinoic acid activates Hoxa1 chromatin - Mus musculus
created	[InstanceEdit:5617923] May, Bruce, 2014-08-16
dbId	5617939
displayName	Rarg:Rxra at Hoxa1 bivalent chromatin [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-MMU-5687969] Ajuba [nucleoplasm] [Complex:R-MMU-5617969] Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-442520] Hdac3 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-5617428] Hoxa1 gene [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-442459] Ncor1 [nucleoplasm] [Complex:R-MMU-5617945] PRC2 (EZH2) [nucleoplasm] [Complex:R-MMU-5617904] Rxra:Rara,g [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-HSA-5617465] RARA,G:RXRA at HOXA1 bivalent chromatin [nucleoplasm] - Homo sapiens
isChimeric	false
literatureReference	[LiteratureReference:5617928] Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells [LiteratureReference:5617936] Retinoic acid-responsive enhancers located 3' of the Hox A and Hox B homeobox gene clusters. Functional analysis [LiteratureReference:5619244] In vivo functional analysis of the Hoxa-1 3' retinoic acid response element (3'RARE) [LiteratureReference:5687914] LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling [LiteratureReference:383069] A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors
maxDepth	5
modified	[InstanceEdit:6810175] May, Bruce, 2015-11-16
name	Rarg:Rxra at Hoxa1 bivalent chromatin
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-5617939
updateTrackers	[UpdateTracker:9897386] Update Tracker - [Complex:5617939] Rarg:Rxra at Hoxa1 bivalent chromatin [nucleoplasm] - v62:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9897386] Update Tracker - [Complex:5617939] Rarg:Rxra at Hoxa1 bivalent chromatin [nucleoplasm] - v62:[updateContainedComponent]
(input)	[BlackBoxEvent:R-MMU-5617990] Retinoic acid activates Hoxa1 chromatin

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