Reactome | lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4]

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lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] Show undefined attributes

authored	[InstanceEdit:548846] D'Eustachio, P, 2010-03-14
catalystActivity	[CatalystActivity:548850] fatty acid elongase activity of Elovl4 [endoplasmic reticulum membrane]
catalystActivityReference	[CatalystActivityReference:9643772] fatty acid elongase activity of Elovl4 [endoplasmic reticulum membrane] Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:548851] D'Eustachio, P, 2010-03-14
dbId	548848
displayName	lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4]
edited	[InstanceEdit:699800] D'Eustachio, P, 2010-05-08
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29508] Mal-CoA [cytosol] [SimpleEntity:R-ALL-548808] TCS-CoA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:548665] Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids [LiteratureReference:548675] Dominant negative mechanism underlies autosomal dominant Stargardt-like macular dystrophy linked to mutations in ELOVL4
maxDepth	1
modified	[InstanceEdit:9910841] D'Eustachio, Peter, 2024-05-21
name	lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4]
orthologousEvent	[Reaction:R-HSA-548830] ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA - Homo sapiens
output	[SimpleEntity:R-ALL-548797] 3OHC-CoA [cytosol] [SimpleEntity:R-ALL-113528] CO2 [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2010-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9907581] Hill, David P, 2024-04-12
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-548848
summation	[Summation:548849] Mouse elongation of very long chain fatty acids protein 4 (E...
updateTrackers	[UpdateTracker:9911086] Update Tracker - [Reaction:548848] lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] - v89:[addInput]

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(updatedInstance)

[UpdateTracker:9911086] Update Tracker - [Reaction:548848] lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] - v89:[addInput]

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