Reactome | GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol

Schema > Reaction > Entries

GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10053990] D-glucose transmembrane transporter activity of GLUT1 / SLC2A1 tetramer [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10053994
displayName	GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol
eventOf	[Pathway:R-MMU-189200] Cellular hexose transport - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:6808140] D-glucose transmembrane transport
inferredFrom	[Reaction:R-HSA-5339524] GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-70115] Glc [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol
output	[SimpleEntity:R-ALL-70113] Glc [cytosol]
precedingEvent	[Reaction:R-MMU-450092] GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP - Mus musculus
regulatedBy	[PositiveRegulation:10053995] Positive regulation by 'FGF21 [extracellular region]' [NegativeRegulation:R-HSA-71507] Negative regulation by 'ATP [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5339524
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-189200] Cellular hexose transport
(inferredTo)	[Reaction:R-HSA-5339524] GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol

Cite Us!