Reactome | CDC42:GTP binds PAK2

Schema > Reaction > Entries

CDC42:GTP binds PAK2 Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10052974
displayName	CDC42:GTP binds PAK2
eventOf	[Pathway:R-MMU-4420097] VEGFA-VEGFR2 Pathway - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-5218814] PAK2 autophorylates - Mus musculus
inferredFrom	[Reaction:R-HSA-5218832] CDC42:GTP binds PAK2 - Homo sapiens
input	2 × [Complex:R-MMU-448879] Cdc42:GTP [plasma membrane] [Complex:R-MMU-5218766] VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN:PAK2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CDC42:GTP binds PAK2
output	[Complex:R-MMU-5218782] VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:PAK2:CDC42:GTP [plasma membrane]
precedingEvent	[Reaction:R-MMU-5218847] PAK2 binds NCK - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5218832
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-4420097] VEGFA-VEGFR2 Pathway
(precedingEvent)	[Reaction:R-MMU-5218814] PAK2 autophorylates
(inferredTo)	[Reaction:R-HSA-5218832] CDC42:GTP binds PAK2

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