Reactome | clathrin:AP-2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-5138437] WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-5138433] p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10051818
displayName	clathrin:AP-2 [plasma membrane]
hasComponent	[Complex:R-MMU-5138439] 3 CLTC:3 CLC triskelion [plasma membrane] [Complex:R-MMU-167712] AP-2 Complex [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5138434] clathrin:AP-2 [plasma membrane] - Homo sapiens
isRequired	[Requirement:10051892] Requirement by 'clathrin:AP-2 [plasma membrane]'
maxDepth	4
name	clathrin:AP-2
positivelyRegulates	[Requirement:10051892] Requirement by 'clathrin:AP-2 [plasma membrane]'
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-5138434
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-5138433] p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis
(hasComponent)	[Complex:R-MMU-5138437] WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane]
(regulator)	[Requirement:10051892] Requirement by 'clathrin:AP-2 [plasma membrane]'
(inferredTo)	[Complex:R-HSA-5138434] clathrin:AP-2 [plasma membrane]