Reactome | Fz3 asymmetric membrane localization depends on direct interaction with Vangl2

Schema > Reaction > Entries

authored	[InstanceEdit:4551590] Rothfels, K, 2013-09-13
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:4608836] Rothfels, K, 2013-09-23
dbId	4608842
displayName	Fz3 asymmetric membrane localization depends on direct interaction with Vangl2
edited	[InstanceEdit:4663813] Matthews, L, 2013-10-07
input	[EntityWithAccessionedSequence:R-MMU-3965366] Fzd3 [plasma membrane] [Complex:R-MMU-4608837] Vangl2:Scrib [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:4608822] Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Fz3 asymmetric membrane localization depends on direct interaction with Vangl2
orthologousEvent	[Reaction:R-HSA-4608866] VANGL2 is required for asymmetric membrane localization of FZD3 - Homo sapiens
output	[Complex:R-MMU-4608841] Scrib:Vangl2:Fzd3 [plasma membrane]
precedingEvent	[Reaction:R-MMU-4608838] Scrib is required for Vangl2 asymmetric membrane localization in mouse - Mus musculus
releaseDate	2013-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5099870] Kikuchi, Akira, 2013-11-12
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-4608842
summation	[Summation:4608840] Fz3 is asymmetrically localized in the membrane of the mouse...

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