Reactome | ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP

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ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP Show undefined attributes

catalystActivity	[CatalystActivity:10017848] N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity of ALG13:ALG14 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10017850
displayName	ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP
eventOf	[Pathway:R-MMU-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-446218] Addition of the first mannose to the N-glycan precursor by ALG1 - Mus musculus
inferredFrom	[Reaction:R-HSA-446207] ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP - Homo sapiens
input	[SimpleEntity:R-ALL-449222] GlcNAcDOLDP [cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:R-ALL-162756] UDP-GlcNAc [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP Addition of the second N-acetyl-glucosamine to the N-glycan precursor
output	[SimpleEntity:R-ALL-449293] N,N'-DCDOLDP [cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:R-ALL-110096] UDP [cytosol]
precedingEvent	[Reaction:R-MMU-446191] Addition of N-acetyl-D-glucosamine to Dolichyl phosphate - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-446207
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
(precedingEvent)	[Reaction:R-MMU-446218] Addition of the first mannose to the N-glycan precursor by ALG1
(inferredTo)	[Reaction:R-HSA-446207] ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP

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